DR. RANGANA SINHA, M.Sc., Ph.D.
Assistant Professor

Education:

 

Ph.D.; Jadavpur University in 1999

M.Sc.; Kalyani University in 1994 (March)

B.Sc.; Kalyani University in 1991

 

Teaching Experience:

 

Assistant Professor, Kandi Raj College, Murshidabad; 2010- till date.

Part Time/ Guest Lecturer, Kanchrapara College, 2002- 2003; 2007-2009.

 

Area of Specialization:

 

Physical Chemistry

 

Research Experience:

 

Post/ Fellowship

Sponsoring Authority

Unidersity/ Institute

Period

 

Pool  Officer /Sr. Res. Associate

Research  Associate

Research  Associate

SRF (extd.)

Project Assistant

 

 

CSIR

ICMR

CSIR

CSIR

UGC

 

 

Ind Inst of Chem  Biology, Kolkata

Ind Inst of Chem  Biology, Kolkata

Ind Inst of Chem  Biology, Kolkata

Jadavpur University, Kolkata

Jadavpur University, Kolkata

 

 

15.01.2010       March  2010

07.12.2007        14.01.2010

17.07.2003      16.07.2007

01.04.1999      31.03.2000

01.03.1995      24.11.1997

 

 

Research Area:

 

Solution Chemistry, Chemical Thermodynamics during Ph.D.work.

 

DNA,RNA Chemistry, Higher Ordered Nucleic Acid (Triplex), Drug-DNA Interaction during Post-Doctoral Period of work..

 

Publications: 

 

1.       Sinha, R., Saha, I. and Suresh Kumar, G. (2011) Protoberberine alkaloids berberine, palmatine, and coralyne binding to poly(dT).poly(dA)*poly(dT) : Comparative structural aspects and energetics of the interaction. Chemistry and Biodiversity 8,1512-1528.

2.       Sinha, R.and Suresh Kumar, G. (2009) Interaction of isoquinoline alkaloids with RNA triplex: Structural and thermodynamic studies of berberine, palmatine, and coralyne binding to poly(U).poly(A)*poly(U).J. Phys. Chem. B 113, 13410-13420.

3.       Sinha, R.*, Hossain, M. and Suresh Kumar, G. (2009) Interaction of small molecules to double stranded RNA: Spectroscopic, viscometric and calorimetric study of hoechst and proflavine binding to poly(C).poly(G) structures. DNA Cell Biol. 28(4): 209-219.

4.       Sinha, R, Hossain, M. and Suresh Kumar, G. (2007) RNA targeting by DNA binding drugs: structural, conformational and energetic aspects of the binding of quinacrine and DAPI to A-form and HL-form of poly(rC).poly(rG). Biochim. Biophys. Acta 1770, 1636-1650.

5.       Islam, Md. M., Sinha, R. and Suresh Kumar, G. (2007) RNA binding small molecules: Studies on t-RNA binding by cytotoxic plant alkaloids berberine, palmatine and comparison to ethidium. Biophys. Chem. 125, 508-520.

6.       Sinha, R., Islam, Md. M.,Bhadra, K., Suresh Kumar, G. and Maiti, M. (2006). Interaction of intercalators and groove binders with A-form and protonated forms of poly(rG).poly(rC). Biorg. Med. Chem.  14, 800-814.

7.       Yadav, R. C., Suresh Kumar, G., Bhadra, K., Sinha, R., Pal, S. and Maiti, M. (2005) Interactions of berberine with single and double stranded polyriboadenylic acid: spectroscopic and thermodynamic study. Biorg. Med. Chem. 13, 165-174.

8. Sinha, R.*, Bhattachrya, S. K. and Kundu, K. K. (2005) Chemical transfer energetics of  –CH2-  group in aqueous glycerol, solvent effect on hydrophobic hydration and its three dimensional structuredness. J. Mol. Liquids 122, 95-103.

9. Sinha, R.*, and Kundu, K. K. (2004) Transfer energetics of a series of homologous a-amino acids and hence of -CH2- group – a possible probe for the solvent effect on hydrophobic hydration and the three-dimensional structuredness of aqueous cosolvents. J. Mol. Liquids 111, 151-159. 

10. Sinha, R., and Kundu, K. K. (1998) Chemicaltransfer energetics of -CH2- group – a possible probe for the solvent effect on hydrophobic hydration and the 3D-structuredness of solvents. J. Phys. Chem., 102, 6880-6888.

11. Sinha, R., and Kundu, K. K. (1998) Transfer Gibbs energies of ATP in aqueous mixtures of nonionic glycerol, urea and ionic NaNO3. Ind. J. Chem. 37A, 789-794. 

12. Sinha, R., and Kundu, K. K. (1998) Transfer energetics of a series of homologous monoalkylammonium ions and hence of -CH2- group – a probe for the solvent effect on hydrophobic hydration and the 3D-structuredness of aqueous cosolvents.Ind. J. Chem., 37A, 780-788. 

13. Sinha, R., and Kundu, K. K. (1998) Transfer energetics of some tetraalkylammonium ions from water to aqueous alkanols: the solvent effect on hydrophobic hydration and the 3D-structuredness of aqueous cosolvents.Ind. J. Chem., 37A, 678-690. 

14. Sinha, R., and Kundu, K. K. (1997) Single–ion transfer energetics in some aqueous alkanols and the structuredness of aquo-organic cosolvents.Ind. J. Chem., 36A, 541-559.

 
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