DR. NILADRI SARKAR, M.Sc.,PhD
Assistant Professor

·                   Date of Joining:                                        01.04. 2015                                                                    

 

                                                   Educational Qualifications

 

         B.Sc.(Honors), Chemistry, R.K.M.R. College, Narendrapur, Calcutta University, Kolkata, India, 1999.

·         M.Sc., Organic Chemistry, Calcutta University, Kolkata, India, 2001.

          Ph.D., Organic Chemistry, Jadavpur University, Kolkata, India, 2008. 

                                                                    Title of Thesis:

                       ‘Synthesis of cyclic compounds with potential biological activity’ 

 

                Research Experience

 

·        2004 – 2007: Senior Research Fellow (CSIR), Indian Association for the Cultivation of Science,                 Jadavpur, Kolkata, India.


 

·        2002 – 2004: Junior Research Fellow (CSIR), Indian Association for the Cultivation of Science,                  Jadavpur, Kolkata, India.

   

 

Developed a new methodology for the synthesis of enantiopure bicyclo[3.2.0]heptane derivatives through copper (I)-catalyzed intramolecular asymmetric [2 + 2] photocycloaddition.A novel anion-induced cleavage of the tetrahydrofuran ring in these oxa-bicyclo[3.2.0]heptane derivatives has led to a convenient access to the synthetically useful cis-1,2-disubstituted cyclobutanes in enantiomerically pure form. Combination of these two protocols has been applied to the formal synthesis of biologically active natural products.

A novel methedology furnishing the highly functionalized cylcohexane derivative using ring closing metathesis (RCM) reaction.

  • [2+2]-Photocycloaddition reaction leading to cyclobutane derivatives in optically pure form.
  • Formal Total Synthesis of (-)-Grandisol and b-Necrodol.
  • Synthesis of Carbahexopyranose in optically pure form through ring closing metathesis (RCM) reaction-Total synthesis of carba-b-L-gulopyranose.

                                                                Award and Fellowships

 

·        Awarded Graduate Aptitude Test in Engineering (GATE-2001).

·        Awarded Doctoral research Fellowship from Council of Scientific and Industrial Research (CSIR), Govt. of India, on the                basis of a nationally competitive examination (NET-2001).

·        Junior Research Fellowship at IACS, kolkata, 2002-2004.

·        Senior Research Fellowship at IACS, Kolkata, 2004- 2007.

                                                          Professional Competence

 

·        Synthesis of highly functionalized biologically active natural products.

·        Application of new reagents / reactions in the field of enantiopure compound synthesis.

·        Development of new methodologies in organic synthesis which have a large scope to be applicable in the total synthesis.

·        Excellent skills in handling air and moisture sensitive reagents and compounds.

·        Purification and identification of organic compounds pertinent to above field.

·        Analysis of routine spectroscopic data such as NMR, IR, UV – visible etc.

·        Exoposure to instruments such as NMR(Brucker, 300 MHz), FTIR(Shimadzu), G.C., Polarimeter etc.

·        Awareness in P.C. operation (MS-DOS, MS-ward, Chem-window etc.).

·        Possession of good communication, management and inter-personal skills.

·        Capable of both independent and collaborative research at ease.

 

                                                             Professional Experience

 

  • Worked  as a Part Time Teacher (Govt. Approv.) in Chemistry in Chemistry Department, Behala College, Parnasree, Behala, Kolkata-700060 from 28.07.2008 to 31.03.2015.
  •  Worked as a Lecturer in chemistry in Biochemistry Department, Gurudas College, Kolkata -700054 from 03.11.2008 to 31.03. 2015
  •  Worked as a Guest Lecturer in Chemistry Department, R.K.M.R. College, Narendrapur in the year 2010-2011and taught “Techniques of Chemical Separation” which included “Fundamentals of Chromatography, Partition Chomatography, paper Chomatography, Thin layer Chomatography, Gas Chomatography, Ion exchange Chomatography, Solvent extraction etc.”  at PG level.

 

                                                                      Publications

 

1.       Copper(I)- Catalyzed Intramolecular Asymmetric [2+2]    Photocycloaddition. Synthesis of Both Enantiomers of           Cyclobutane Derivatives - Niladri Sarkar, Abhijit Nayek and Subrata Ghosh, Org. Lett. 2004, 6, 1903.

2.       Factors Influencing Ring Closure through Olefin Metathesis – A Perspective- Subrata Ghosh, Sarita Ghoshand           Niladri Sarkar, J. Chem. Sci.2006, 118, 223.

3.       Asymmetric induction in copper (I)-catalyzed intramolecular [2 + 2] photocycloaddition: Synthesis of                              enantiopure cyclobutane derivatives - Niladri Sarkar and Subrata Ghosh, Indian J. Chem. 2006, 45B, 2474.

4.    A Convenient Approach for Access to Both Carbapentofuranoses and Carbahexo-pyranoses. Stereocontrolled          Synthesis of Enantiopure Carba-D-ribofuranoses, Carba-D-arabinofuranoses and Carba-L-gulopyranose-              Subrata  Ghosh, Tanurima Bhaumik, Niladri Sarkar and Abhijit Nayek, J. Org. Chem. 2006, 71, 9687.

 
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