|DR. NILADRI SARKAR, M.Sc.,PhD|
· Date of Joining: 01.04. 2015
B.Sc.(Honors), Chemistry, R.K.M.R. College, Narendrapur, Calcutta University, Kolkata, India, 1999.
· M.Sc., Organic Chemistry, Calcutta University, Kolkata, India, 2001.
Ph.D., Organic Chemistry, Jadavpur University, Kolkata, India, 2008.
Title of Thesis:
‘Synthesis of cyclic compounds with potential biological activity’
· 2004 – 2007: Senior Research Fellow (CSIR), Indian Association for the Cultivation of Science, Jadavpur, Kolkata, India.
· 2002 – 2004: Junior Research Fellow (CSIR), Indian Association for the Cultivation of Science, Jadavpur, Kolkata, India.
Developed a new methodology for the synthesis of enantiopure bicyclo[3.2.0]heptane derivatives through copper (I)-catalyzed intramolecular asymmetric [2 + 2] photocycloaddition.A novel anion-induced cleavage of the tetrahydrofuran ring in these oxa-bicyclo[3.2.0]heptane derivatives has led to a convenient access to the synthetically useful cis-1,2-disubstituted cyclobutanes in enantiomerically pure form. Combination of these two protocols has been applied to the formal synthesis of biologically active natural products.
A novel methedology furnishing the highly functionalized cylcohexane derivative using ring closing metathesis (RCM) reaction.
Award and Fellowships
· Awarded Graduate Aptitude Test in Engineering (GATE-2001).
· Awarded Doctoral research Fellowship from Council of Scientific and Industrial Research (CSIR), Govt. of India, on the basis of a nationally competitive examination (NET-2001).
· Junior Research Fellowship at IACS, kolkata, 2002-2004.
· Senior Research Fellowship at IACS, Kolkata, 2004- 2007.
· Synthesis of highly functionalized biologically active natural products.
· Application of new reagents / reactions in the field of enantiopure compound synthesis.
· Development of new methodologies in organic synthesis which have a large scope to be applicable in the total synthesis.
· Excellent skills in handling air and moisture sensitive reagents and compounds.
· Purification and identification of organic compounds pertinent to above field.
· Analysis of routine spectroscopic data such as NMR, IR, UV – visible etc.
· Exoposure to instruments such as NMR(Brucker, 300 MHz), FTIR(Shimadzu), G.C., Polarimeter etc.
· Awareness in P.C. operation (MS-DOS, MS-ward, Chem-window etc.).
· Possession of good communication, management and inter-personal skills.
· Capable of both independent and collaborative research at ease.
1. Copper(I)- Catalyzed Intramolecular Asymmetric [2+2] Photocycloaddition. Synthesis of Both Enantiomers of Cyclobutane Derivatives - Niladri Sarkar, Abhijit Nayek and Subrata Ghosh, Org. Lett. 2004, 6, 1903.
2. Factors Influencing Ring Closure through Olefin Metathesis – A Perspective- Subrata Ghosh, Sarita Ghoshand Niladri Sarkar, J. Chem. Sci.2006, 118, 223.
3. Asymmetric induction in copper (I)-catalyzed intramolecular [2 + 2] photocycloaddition: Synthesis of enantiopure cyclobutane derivatives - Niladri Sarkar and Subrata Ghosh, Indian J. Chem. 2006, 45B, 2474.
4. A Convenient Approach for Access to Both Carbapentofuranoses and Carbahexo-pyranoses. Stereocontrolled Synthesis of Enantiopure Carba-D-ribofuranoses, Carba-D-arabinofuranoses and Carba-L-gulopyranose- Subrata Ghosh, Tanurima Bhaumik, Niladri Sarkar and Abhijit Nayek, J. Org. Chem. 2006, 71, 9687.
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